Granular cell tumor of the breast: a case report and review of literature
نویسندگان
چکیده
A 22-year-old female patient presented with a breast mass lesion with a clinical suspicion of a fibroadenoma. Histological evaluation revealed a rare benign neoplasm - granular cell tumor.Granular cell tumor is rare neoplasm that may arise in virtually any body site, and in 5% it occurs in the breast. The histogenesis of this tumor is still rather controversial and currently the most acceptable theory is a Schwann cell origin. The main histological feature is granular cytoplasm of the tumor cells.From a clinical point of view there is a similarity between granular cell tumor and mammary carcinoma on mammography and ultrasound. Pathohistologically, sometimes, differential diagnostic difficulties exist concerning apocrine carcinoma, histiocytic lesions and metastatic neoplasms.
منابع مشابه
A Rare Case of Benign Granular Cell Tumor of the Breast
Granular cell tumor is a rare benign non-encapsulated tumor that mostly presents in oral cavity. Breast localization is uncommon and occurs in about one per 1000 cases of breast cancers. It mainly affects premenopausal women showing the possible role of estrogen and progesterone levels in the progression of this tumor. Granular cell tumor is a great emulator of the invasive ductal carcinoma of ...
متن کاملCoexistence of Granular Cell Tumor with Squamous Cell Carcinoma on the Tongue: A Case Report
Introduction: Granular cell tumors (GCTs) are rare and mostly benign soft tissue tumors. Though they have been reported in all parts of body, they are generally located in the head and neck region, especially on the tongue. Some malign forms exist, but these have been rarely reported. Granular cell tumors have a neural origin and, in immunohistochemical evaluations, they express S-100 and neuro...
متن کاملSynchronous lingual granular cell tumor and squamous cell carcinoma (case report)
Synchronous lingual granular cell tumor and squamous cell carcinoma (case report) Dr. D. Sadri* *-Assistant Professor of Oral & Maxillofacial Pathology Dept. – Faculty of Dentistry – Tehran Islamic Azad University. Introduction: For the first time, Abrikossof described granular cell tumor in 1926. It was firstly believed that this tumor originated from skeletal muscle but using electron microsc...
متن کاملSclerosing Sertoli Cell Tumor of the Testis: Case Report and Review of the Literature
Sertoli cell tumors of the testis are extremely rare tumors with a heterogeneous pathology. Three histological variants have been described: Sertoli cell tumor not otherwise specified (NOS), large cell calcifying sertoli cell tumor and the Sclerosing Sertoli cell tumor. The sclerosing Sertoli cell tumor described herein is associated with prominent stromal sclerosis. They present as painless...
متن کاملGiant Cell Reparative Granuloma (G.C.R.G) of the Maxillary Sinus (Brown Tumor): a Case Report and Review of Literature
The patient is a seventheen years old girl, with severe pain and swelling in right maxillary sinus region and facial deformity from two weeks prior to referring. CT scan demonstrated a large tumoral mass in right maxillary sinus extended to petereigomaxillary fossa, orbital floor, lacrimal system and nasoethmoid region. Hard palate had been destroyed and bulged in to the oral cavity. Tumor was ...
متن کاملGiant cell tumor of patella: A case report and review of literature
Objective: Patella is a sesamoid bone which develops in the quadriceps tendon. It is an uncommon site for neoplasms. The most common primary tumors which involve patella are benign. These include chondroblastoma, giant cell tumor (GCT) and aneurysmal bone cyst. Malignant lesions are less common in patella. These encompass metastasis, osteosarcoma and hemangioendothelioma. The most common compla...
متن کامل